Gli studi trascrittomici condotti dal team di Pickart e Campbell hanno costituito una svolta importante rivelando l'ampiezza dell'azione genomica di GHK-Cu
Results: Supplementing with H 2 by intraperitoneal injection protected MCD diet-fed mice against hepatic steatosis and fibrosis by down-regulating de novo lipogenesis and fatty acid uptake genes, as well as hepatic Collagen- and Collagen- protein levels, while up-regulating lipid export genes
The proposed mechanism of action of these peptides is that they enter the hind-brain from the peripheral bloodstream, and interact directly with GLP-1 receptors in the brain - possibly the parabrachial nucleus (Kanoski et al., 2016)
Chung, B ., Choi, S., Moon, I., Park, C., Kim, Y.-H